由自然出版集團出版。ISSN: 1359-4184。發表旨在闡明精神疾病及其治療的生物學機制的工作。重點是臨床前研究和臨床研究的銜接，包括細胞、分子、整合、臨床、影像學和精神藥理學水平的研究。

Published by Nature Publishing Group. ISSN: 1359-4184.Publishes work aimed at elucidating biological mechanisms underlying psychiatric disorders and their treatment. The emphasis is on studies at the interface of pre-clinical and clinical research, including studies at the cellular, molecular, integrative, clinical, imaging and psychopharmacology levels.