該雜志為寄生蟲原生動物和蠕蟲的分子生物學和生物化學研究及其與最終宿主和中間宿主的相互作用的快速出版提供了一個媒介。所涵蓋的主要范疇包括:?DNA、RNA、蛋白質、脂類、碳水化合物和小分子量物質的結構、生物合成、降解、性質和功能?中間代謝和生物能學?藥物靶點表征及抗寄生蟲藥物的作用模式?膜結構和功能的分子和生化方面?寄主-寄主關系，主要關注寄主，特別是與特定的寄主分子相關的寄主-寄主關系。?基因和基因組結構、功能和表達分析?分析寄生蟲種群中與基因交換、發病機制、藥物和疫苗靶點表征以及耐藥性相關的變異。?寄生蟲蛋白的轉運、細胞器的生物發生和細胞結構，特別是特定分子的作用?寄生蟲在分子水平上對細胞的死亡、發育和分裂進行程序化處理只有當論文屬于這些領域，如果它們包含有高科學質量的原創和完整的作品，并且呈現得很好，才會被接受發表。僅證實以前在其他生物體中研究過的基因的保守功能的論文將不予考慮。此外，以下工作領域更適合于其他期刊:?主要關注宿主反應的研究(如免疫學)?調查報告等位基因或應變頻率在不同地區?在沒有生物實驗的硅模型或計算工作中?報告與生物學無關的等位基因或菌株頻率的調查(例如，耐藥性或發病機制)

The journal provides a medium for rapid publication of investigations of the molecular biology and biochemistry of parasitic protozoa and helminths and their interactions with both the definitive and intermediate host. The main subject areas covered are:? the structure, biosynthesis, degradation, properties and function of DNA, RNA, proteins, lipids, carbohydrates and small molecular-weight substances? intermediary metabolism and bioenergetics? drug target characterization and the mode of action of antiparasitic drugs? molecular and biochemical aspects of membrane structure and function? host-parasite relationships that focus on the parasite, particularly as related to specific parasite molecules.? analysis of genes and genome structure, function and expression? analysis of variation in parasite populations relevant to genetic exchange, pathogenesis, drug and vaccine target characterization, and drug resistance.? parasite protein trafficking, organelle biogenesis, and cellular structure especially with reference to the roles of specific molecules? parasite programmed cell death, development, and cell division at the molecular levelPapers will only be accepted for publication if they fall within these areas, if they contain original and complete work of high scientific quality, and if they are well presented. Papers solely confirming the conserved functions of genes previously studied in other organisms will not be considered.Additionally the following areas of work are better suited to other journals:? studies predominantly focused on the host response (e.g. immunology) ? surveys reporting allele or strain frequencies in various regions ? in silico modeling or computational work without biological experiments ? surveys reporting allele or strain frequencies not linked to biological relevance (e.g., drug resistance, or pathogenesis)